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Arsenic trioxide uses

The active substance in Trisenox, arsenic trioxide, is a chemical that has been used in medicines for many years, including for the treatment of leukaemia. The way it works in this disease is not completely understood. It is thought to prevent the production of DNA, which is necessary for leukaemia cells to grow. Arsenic trioxide is used to treat a cancer of the blood and bone marrow called acute promyelocytic (pro-MYE-loe-SIT-ik) leukemia, or APL. Arsenic trioxide is sometimes given in combination with another medicine called tretinoin. Arsenic trioxide may also be used for other purposes not listed in this medication guide. diarsenic trioxide; arsenic trioxide . FCM Active and Intelligent Materials - CMRs not allowed for use, CAD - Chemical Agents Directive, Art. 2(b)(i) Arsenic trioxide medac is used to treat adults (aged 18 years or over) with acute promyelocytic leukaemia (APL).

Thomas Fowler's potassium bicarbonate‐based solution of arsenic trioxide (As 2 O 3) was used empirically to treat a variety of disorders, and in 1878, was reported to reduce white blood cell counts in two normal individuals and one with “leucocythemia.” Arsenic and its compounds, especially the trioxide, are used in the production of pesticides, treated wood products, herbicides, and insecticides. These applications are declining with the increasing recognition of the toxicity of arsenic and its compounds. A few species of bacteria are able to use arsenic compounds as respiratory metabolites.

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“Many pharmaceutical companies are developing anticancer drugs to inhibit the Hedgehog pathway,” said Philip Beachy , PhD, professor of developmental biology and the Ernest and Amelia Gallo Professor in the School of Medicine. Arsenic Trioxide Sodium Hydroxide water Chemwatch: 23-0970 Version No: 6.1.1.1 Page 2 of 9 Phenasen®, Arsenic Trioxide, 10mg In 10ml, Injection Issue Date: 10/07/2017 Print Date: 02/03/2018 Continued Arsenic is a trace element. Learn more about Arsenic uses, benefits, side effects, interactions, safety concerns, and effectiveness. USES: Arsenic trioxide is used to treat a type of leukemia (acute promyelocytic leukemia-APL).

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Arsenic trioxide is used to treat a cancer of the blood and bone marrow called acute promyelocytic (pro-MYE-loe-SIT-ik) leukemia, or APL. Arsenic trioxide is sometimes given in combination with another medicine called tretinoin. Arsenic trioxide may also be used for other purposes not listed in this medication guide.
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Before using this medication you need to tell your doctor: if you have any allergies to any substances in Chemical name : diarsenic trioxide, arsenic trioxide CAS No : 1327-53-3 Product code : LC11505 Formula : As2O3 Synonyms : Arsenous acid / Arseni c (III) oxide / Diarsenic trioxide 1.2. Relevant identified uses of the substance or mixture and uses advised against Use of the substance/mixture : For laboratory and manufacturing use only. When in its trioxide form, arsenic is used to treat asthma.

In Traditional Chinese Medicine, arsenous acid or arsenic trioxide paste is often used to treat tooth marrow disease as a devitalizing agent. Arsenic trioxide was first purified and used in controlled studies in China in the 1970s.Subsequently, randomised clinical trials performed in the United States led to FDA approval of arsenic trioxide in the treatment of patients with relapsed or refractory acute promyelocytic leukaemia. Chemical name : diarsenic trioxide, arsenic trioxide CAS No : 1327-53-3 Product code : LC11505 Formula : As2O3 Synonyms : Arsenous acid / Arseni c (III) oxide / Diarsenic trioxide 1.2.
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Hazardous Substances Data Bank (HSDB) Arsenic trioxide should be used under the supervision of a qualified clinician experienced in the management of patients with acute leukemia. American Society of Health System Pharmacists. AHFS Drug Information 2008. Bethesda, Maryland 2008, p.

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Arsenic Trioxide (Trisenox) Last Updated: November 6, 2020 Arsenic trioxide is used to treat a cancer of the blood and bone marrow called acute promyelocytic (pro-MYE-loe-SIT-ik) leukemia, or APL. 2021-04-02 · Arsenic Trioxide is used for Blood Cancer, Acute Promyelocytic Leukemia etc. Know Arsenic Trioxide uses, side-effects, composition, substitutes, drug interactions, precautions, dosage, warnings only on Lybrate.com Arsenic has been used as a medicinal for thousands of years. Several reports from China relative to its use mainly in acute promyelocytic leukemia, especially from the Shanghai group, has caused a resurgence in the investigation of the drug in the management of malignancies with focus on malignancie … Arsenic Trioxide - 2 - Ingestion: May be fatal if swallowed. Causes severe digestive tract burns with abdominal pain, vomiting, and possible death.

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Se hela listan på reference.medscape.com Arsenic Trioxide - 4 - OSHA Vacated PELs: Arsenic trioxide: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Se hela listan på gov.uk 2021-04-16 · Arsenic trioxide may harm the fetus. tell your doctor if you are breastfeeding. Your doctor will probably tell you not to breastfeed during your treatment and for 2 weeks after your final dose. you should know that this medication may decrease fertility in men.

As an industrial chemical, major uses include in the manufacture of wood preservatives, pesticides, and glass. As a medication it is used to treat a type of cancer known as acute promyelocytic leukemia. Arsenic trioxide is approved to be used with tretinoin to treat: Acute promyelocytic leukemia (APL) in patients whose cancer has a certain type of chromosome mutation that affects the PML gene and RARA gene. In some cases, health care professionals may use the trade name Trisenox® when referring to the generic drug name Arsenic Trioxide.